Propofol is an intravenous sedative hypnotic used for induction and maintenance of anesthesia. The onset time of induction anesthesia is 75-120s. The average duration of anesthesia was 6.7 minutes after induction dose of propofol. After the administration of propofol, the average duration of anesthesia was 3.68 min; The average duration of anesthesia was 3.80 min in dogs given acepromazine before anesthesia; The average duration of anesthesia was 5.43 min in the dogs given acepromazine / hydromorphone before anesthesia. The recovery of propofol anesthesia is rapid, generally within 20 minutes, the animals can fully recover standing, and the recovery time of animals given propofol before anesthesia may be prolonged.